Right after calling (oos 'load-op :fomus-test), you should be able to do (fomus-test:run-tests). If you would like to update the checksums for all failures, then set fomus-test:*MD5-LEARN-CHECKSUMS* to T, before calling (fomus-test:run-tests). To update an individual test e.g. you could invoke: (5am:run! 'fomus-test::simple-scale.2) And of course, collections of tests can be called as well, if they have been declared with (in-suite ...).